Tallaabooyin faahfaahsan oo ku saabsan sida loo isticmaalo microspheres embolic

Microspheres-ka Embolic waa microspheres hydrogel ah oo la cadaadin karo oo leh qaab caadi ah, dusha siman, iyo cabbir la cabbiray, kuwaas oo ka dhasha wax ka beddelka kiimikada ee walxaha polyvinyl alcohol (PVA). Microspheres-ka Embolic waxay ka kooban yihiin macromer laga soo qaatay alcohol polyvinyl (PVA), waana hydrophilic, lama nuugo karo, waxaana laga heli karaa cabbirro kala duwan. Xalka ilaalinta waa xalka 0.9% sodium chloride. Biyaha ku jira microsphere-ka si buuxda loo polymerized waa 91% ~ 94%. Microspheres-ku waxay u dulqaadan karaan cadaadiska 30%.

Microspheres-ka Embolic waxaa loogu talagalay in loo isticmaalo embolization-ka arteriovenous malformations (AVMs) iyo burooyinka hypervascular, oo ay ku jiraan fibroids-ka ilmo-galeenka. Marka la xiro socodka dhiigga ee aagga la beegsanayo, burooyinka ama cilladaha ayaa ka gaajoonaya nafaqooyinka waxayna yareeyaan cabbirka.

Maqaalkan, waxaan ku tusi doonaa tallaabooyinka faahfaahsan ee ku saabsan sida loo isticmaalo Microspheres-ka Embolic.

Diyaarinta alaabta

Waxaa lagama maarmaan ah in la diyaariyo 1 sirinji oo 20ml ah, 2 sirinji oo 10ml ah, 3 sirinji oo 1ml ama 2ml ah, maqasyo qalliin oo saddex-geesood ah, koob nadiif ah, daawooyinka kiimoterabiga, microspheres embolic, dhexdhexaadin isbarbardhig ah, iyo biyo la isku duro.

Tallaabada 1: Habbee daawooyinka kiimoterabiga

Isticmaal maqas qalliin si aad u furto dhalada daawada kiimikada oo aad daawada kiimikada ku shubto koob nadiif ah.
Nooca iyo qiyaasta daawooyinka kiimoterabiga waxay ku xiran tahay baahiyaha caafimaad.

Biyo u isticmaal duritaanka si aad u milmiso daawooyinka kiimoterabiga, tirada lagu taliyayna waa in ka badan 20mg/ml.

AKa dib markii daawada kiimoterabiga si buuxda loo milmay, xalka daawada kiimoterabiga waxaa lagu soo saaray sirinj 10ml ah.

Tallaabada 2: Soo saarista microspheres-ka embolic-ka ee sida daroogada

Microspheres-kii la sameeyay ayaa si buuxda loo ruxay, waxaana la geliyay irbad sirinji ah si loo dheellitiro cadaadiska ku jira dhalada,oo ka soo saar xalka iyo microspheres-ka dhalada cillin adigoo isticmaalaya sirinji 20ml ah.

Cirbadda ha istaagto 2-3 daqiiqo, ka dib marka microspheres-ku ay degaan, dareeraha ayaa laga saarayaa xalka.

Tallaabada 3: Daawooyinka kiimoterabiga ku rid Microspheres-ka Embolic

Isticmaal 3-da dariiq ee stopcock si aad ugu xirto sirinjiyaha microsphere-ka embolic iyo sirinjiyaha daawada kiimoterabiga, fiiro gaar ah u yeelo xiriirka iyo jihada socodka.
Hal gacan ku riix irbadda daawada kiimoterabiga, oo gacanta kale ku jiid irbadda ay ku jiraan microspheres-ka embolic. Ugu dambeyntii, daawada kiimoterabiga iyo microsphere-ka waxaa lagu qasaa irbad 20ml ah, si fiican u rux irbadda, oo u daa 30 daqiiqo, rux 5tii daqiiqoba mar inta lagu jiro caadada.

Tallaabada 4: Ku dar warbaahinta isbarbardhigga ah

Ka dib markii microspheres-ka lagu shubay daawooyin kiimoterabiga ah muddo 30 daqiiqo ah, mugga xalka ayaa la xisaabiyay.
Ku dar 1-1.2 jeer mugga wakiilka isbarbardhigga iyada oo loo marayo stopcock-ka saddex-geesoodka ah, si fiican u rux oo u daa 5 daqiiqo.

Tallaabada 5: Microspheres waxaa loo isticmaalaa habka TACE

Iyada oo loo marayo stopcock-ka saddex-geesoodka ah, ku dur qiyaastii 1ml oo microspheres ah sirinjka 1ml.

Microspheres-ka waxaa lagu duray microcatheter-ka iyadoo la adeegsanayo duritaan garaac ah.

Hagaha dareenka:

Fadlan hubi in qalliinka aseptic-ga la sameeyo.
Xaqiiji in daawooyinka kiimoterabiga ah ay gebi ahaanba milmaan ka hor inta aan la rarin daawooyinka.
Fiirsashada daawooyinka kiimoterabiga waxay saameyn doontaa saameynta rarista daawada, iyadoo heerka sare ee fiirsashada, heerka nuugista oo dhakhso badan, fiirsashada rarista daawada ee lagu taliyay kama yaraan 20mg/ml.
Biyo nadiif ah oo keliya oo loogu talagalay duritaanka ama 5% gulukoos ayaa loo isticmaali karaa in lagu milmo daawooyinka kiimoterabiga.
Heerka kala dirista doxorubicin ee biyo nadiif ah oo la isku duro wuxuu ahaa mid ka dhakhso badan 5% duritaanka gulukooska.
5% duritaanka gulukooska ayaa milaxisa pirabucin si ka dhakhso badan biyaha nadiifka ah ee la isku duro.
Isticmaalka ioformol 350 oo ah dhexdhexaad ka duwan ayaa aad ugu habboonaa joojinta microspheres.
Marka burooyinka lagu duro iyada oo loo marayo microcatheter, waxaa la isticmaalaa duritaanka garaaca wadnaha, taas oo aad ugu habboon suspension-ka microsphere.