tillaabooyin faahfaahsan oo ku saabsan sida loo isticmaalo microspheres embolic

Embolic Microspheres waa microspheres hydrogel oo la isku cadaadi karo oo leh qaab joogto ah, oog siman, iyo cabbir la suubiyey, kuwaas oo loo sameeyay natiijada wax ka beddelka kiimikaad ee alkolada polyvinyl (PVA). Embolic Microspheres waxay ka kooban yihiin makromer laga soo dheegtay alkolada polyvinyl (PVA), waana hydrophilic, aan dib loo celin karin, waxaana lagu heli karaa cabbirro kala duwan. Xalka ilaalinta waa 0.9% sodium chloride. Mawduuca biyaha ee microsphere buuxa ee polymerized waa 91% ~ 94%. Microspheres waxay u dulqaadan karaan cadaadis 30%.

Microspheres Embolic waxaa loogu talagalay in loo isticmaalo hufnaanta cilladaha arteriovenous (AVMs) iyo burooyinka hypervascular, oo ay ku jiraan fibroids uterineine. Marka la xannibo bixinta dhiigga aagga la beegsanayo, burada ama qaab-dhismeedku waxay ka gaajoonayaan nafaqooyinka oo way yaraanayaan cabbirkooda.

Maqaalkan, waxaan ku tusi doonaa tillaabooyinka faahfaahsan ee ku saabsan sida loo isticmaalo Embolic Microspheres.

Diyaarinta alaabta

Waa lagama maarmaan in la diyaariyo 1 20ml sirinji, 2 10ml sirinjiye, 3 1ml ama 2ml sirinjiye, saddex-jid, maqas qalliin, koob nadiif ah, daawooyinka kiimoterabiga, microspheres embolic, ka soo horjeeda warbaahinta, iyo biyaha duritaanka.

Talaabada 1: Habee daawooyinka kiimoterabiga

Isticmaal maqas qalliin si aad u furto dhalada daawaynta kimoterapeutic oo aad ku shubto dawada kemotherabi koob nadiif ah.
Nooca iyo qiyaasta daawooyinka kemotherabi waxay ku xiran tahay baahida caafimaad.

U isticmaal biyaha duritaanka si aad u milmaan daawooyinka kiimoterabiga, iyo xoogga lagu taliyey waa in ka badan 20mg/ml.

AKa dib markii daawada kiimikaad si buuxda u milmay, xalka daawada kiimikaad waxaa lagu soo saaray siringe 10ml ah.

Talaabada 2: Soo saarida daawada-sida microspheres

Microspheres-ka la qurxiyey ayaa si buuxda loo ruxay, waxaana la geliyey irbad silingaha si loo dheellitiro cadaadiska dhalada,oo ka soo saar xalalka iyo microspheres dhalada cillin leh sirinji 20ml ah.

U ogolow saliinguhu inuu istaago 2-3 daqiiqo, ka dib marka microspheres ay dejiyaan, supernatant ayaa laga riixayaa xalka.

Tallaabada 3: Ku shub dawooyinka kiimikaad ee Embolic Microspheres

Isticmaal 3da siyaabood ee cock-ka-joojinta si aad ugu xidhid saliingaha leh microsphere-ka emboliska iyo saliingaha leh dawada kemotherabi, u fiirso xidhiidhka si adag iyo jihada socodka.
Hal gacan ku riix saliingaha dawada kemotherabi, oo gacanta kale ku soo jiid saliingaha ka kooban microspheres embolism. Ugu dambeyntii, dawada kemotherabi iyo microsphere ayaa lagu qasi karaa sirinji 20ml ah, si fiican u rux saliingaha, ka dibna u daa 30 daqiiqo, rux 5tii daqiqo kasta inta lagu jiro xilliga caadada.

Talaabada 4: Ku dar warbaahinta ka duwan

Ka dib markii microspheres-ka lagu shubay daawooyinka kiimikaad ee 30 daqiiqo, mugga xalka ayaa la xisaabiyay.
Ku dar 1-1.2 jeer mugga wakiilka isbar-bardhigga iyada oo loo marayo seddexda dariiq ee istaagida, si fiican u rux oo u ogolow 5 daqiiqo.

Talaabada 5: Microspheres waxaa loo isticmaalaa habka TACE

Iyada oo loo marayo seddexda dariiq ee stopcock, ku dur qiyaastii 1ml oo microspheres ah saliingaha 1ml.

Microspheres-ka waxaa lagu duray microcatheter iyadoo la duray garaaca wadnaha.

Hagaa dareenka:

Fadlan hubi hawlgalka aseptic.
Xaqiiji in dawooyinka kemotherabi ay si buuxda u milmeen ka hor inta aan la saarin daawooyinka.
Xoojinta dawooyinka kemotherabi waxay saamayn doontaa saamaynta rarka daroogada, korodhka feejignaanta, dhakhsaha badan ee heerka xayeysiinta, xoojinta daawada lagu taliyey kama yarayn 20mg/ml.
Kaliya biyaha nadiifka ah ee duritaanka ama 5% duritaanka gulukooska waa in la isticmaalo si loo milo daawooyinka kiimoterabiga.
Heerka milanka doxorubicin ee biyaha nadiifka ah ee duritaanka ayaa waxyar ka dhaqso badan 5% duritaanka gulukooska.
5% duritaanka gulukoosta waxay milaan pirarubicin wax yar ka dhaqso badan biyaha nadiifka ah ee duritaanka.
Isticmaalka ioformol 350 sida dhexdhexaadinta isbarbardhigga ayaa aad ugu habboon joojinta microspheres.
Marka lagu duro burada iyada oo loo marayo microcatheter, cirbadeynta garaaca wadnaha ayaa la isticmaalaa, taas oo aad ugu habboon joojinta microsphere.